I’ve loved Joseph Gordon-Levitt ever since he played the sweet and vulnerable guy in 500 Days of Summer. In 50/50 he plays a young man diagnosed with spinal cancer who bonds with his best pal played by Seth Rogen who helps him through the chemo and the tough diagnosis with heart and humor. In real life, Rogen’s best friend went through this harrowing scenario and he asked his pal, now in remission, to write the screenplay. Poignant and funny.